## Abstract Tight junctions as an epithelial barrier against paracellular diffusion have mainly been investigated on the protein level with particular respect to subcellular localization. In this study, realβtime PCR has been established to investigate the influence of protein kinase C (PKC) modula
β¦ LIBER β¦
The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton
β Scribed by Fanning, A. S.
- Book ID
- 111986712
- Publisher
- The American Society for Biochemistry and Molecular Biology
- Year
- 1998
- Tongue
- English
- Weight
- 563 KB
- Volume
- 273
- Category
- Article
- ISSN
- 0021-9258
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## Abstract The formation of a barrier by tight junctions is important in epithelia of various tissues. Substance P (SP) and insulinβlike growth factor (IGF)β1 synergistically promote barrier function in the corneal epithelium. We have now examined the effects of SP and IGFβ1 on expression of the t