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The Thyroid-Stimulating Hormone Receptor: Impact of Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Antibodies on Multimerization, Cleavage, and Signaling

✍ Scribed by Latif, Rauf; Morshed, Syed A.; Zaidi, Mone; Davies, Terry F.

Book ID
121954219
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
459 KB
Volume
38
Category
Article
ISSN
0889-8529

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The thyroid-stimulating hormone receptor (TSHR) is an integral membrane glycoprotein which forms a binding site for TSH on the outside surface of thyroid follicular cells. The level of expression of the TSHR on the cell surface is very low (in the region of 1000-10000 sites per cell) and consequentl