𝔖 Bobbio Scriptorium
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The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

✍ Scribed by Martin, Carol B; Mahon, Gwendolyn M; Klinger, Mark B; Kay, Robert J; Symons, Marc; Der, Channing J; Whitehead, Ian P


Book ID
110064572
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
568 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract Factor Xa (FXa) elicits intracellular signaling responses through the activation of protease‐activated receptor 2 (PAR2) and possibly also through PAR1 in endothelial cells. In this study, we investigated FXa signaling in endothelial cells when the protease was either in free form or as