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The Thorpe-Ingold Effect in Glutarimide Derivatives. Part II

✍ Scribed by Czarnocki, Zbigniew; Pawlowski, Michal; K. Maurin, Jan; Leniewski, Andrzej; Wojtasiewicz, Krystyna

Book ID
111922265
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
549 KB
Volume
65
Category
Article
ISSN
0385-5414

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The use of Cu(OTf) 2 as a catalyst for tandem hydroalkoxylation-hydroarylation reaction of alkynes tethered with hydroxyl group is reported. The reaction proceeds at 60 °C or even at room temperature with 5 mol % catalyst loading and produces C-3-substituted indoles in good to high yields. The metho