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The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the α-Glycosylation of Primary Hydroxy Groups

✍ Scribed by Chung-Shan Yu; Kenichi Niikura; Chun-Cheng Lin; Chi-Huey Wong


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
112 KB
Volume
40
Category
Article
ISSN
0044-8249

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✦ Synopsis


5-Azido sialyl donors with O-acetyl protecting groups are useful α-selective glycosylation reagents, especially for primary hydroxyl groups as acceptors. This is shown with a variety of reactions using 1 as a sialyl donor. It was also possible to synthesize NeuAcα(2→9)NeuAc as a thioglycoside donor for use in subsequent glycosylations.


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ChemInform Abstract: The Thioglycoside a
✍ Chung-Shan Yu; Kenichi Niikura; Chun-Cheng Lin; Chi-Huey Wong 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 1 views

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