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The thermolysin-catalyzed condensation reactions of n-substituted aspartic and glutamic acids with phenylalanine alkyl esters

✍ Scribed by Yoshikazu Isowa; Muneki Ohmori; Tetsuya Ichikawa; Kaoru Mori; Yuji Nonaka; Kei-ichi Kihara; Kiyotaka Oyama; Heijiro Satoh; Shigeaki Nishimura


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
152 KB
Volume
20
Category
Article
ISSN
0040-4039

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Nitriles under palladium-catalyzed hydro
✍ FranΓ§oise HΓ©nin; StΓ©phane LΓ©tinois; Jacques Muzart πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 218 KB

At room temperature, the presence of hydrogen and catalytic amounts of Pd/C induced the formation of 1,3-oxazolidines from nitriles and 1,2-amino alcohols. The subsequent reductive cleavage of the NC-O bond of lhese heterocycles occurred under the same conditions. Thus, this methodology provides a n