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The thermodynamics of protein stability: Cold destabilization as a general phenomenon

✍ Scribed by F. Franks; R.H.M. Hatley; H.L. Friedman

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
820 KB
Volume
31
Category
Article
ISSN
0301-4622

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A st at ist ical t ho-m odjw a m ic t heor.)> is developed t o in vat igat e t h 6) c ffivts Q f soliit c> e.xclz4ded voliime on the stability cf globiilur proteins. Proteins are moddcd as two states in chemical eqiiilibrizim: the denatirred state is modeled as ajle.xible chain of tungent hard spher