✦ LIBER ✦

The Thermodynamics of Phosphate versus Phosphorothioate Ester Hydrolysis.

✍ Scribed by Jamie Purcell; Alvan C. Hengge

Publisher: John Wiley and Sons
Year: 2006
Weight: 8 KB
Volume: 37
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200603169

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ascorbic acid catalyzed hydrolysis of ph

Ascorbic acid catalyzed hydrolysis of phosphate esters

✍ Megumi Eda Maejima; Gordon C. Kresheck 📂 Article 📅 1971 🏛 Elsevier Science 🌐 English ⚖ 585 KB

## Previous work of Hansson and Rasmusson (1) has shown that low concentrations (lO-' M) of ascorbic acid enhance the rate of purified milk acid phosphatase catalyzed hydrolysis of phenyl phosphate by 500/o, and that higher concentrations of ascorbic acid (lo-'M) are completely inhibitory. It was

Associative Versus Dissociative Mechanis

Associative Versus Dissociative Mechanisms of Phosphate Monoester Hydrolysis: On the Interpretation of Activation Entropies

✍ Shina C. L. Kamerlin; Jan Florián; Arieh Warshel 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

ChemInform Abstract: Cycloplatinated Ary

ChemInform Abstract: Cycloplatinated Aryl Ketoximes as Efficient Biomimicking Catalysts for Hydrolysis of Esters of Phosphorothioic Acid.

✍ G. M. Kazankov; V. S. Sergeeva; A. A. Borisenko; A. I. Zatsman; A. D. Ryabov 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

Prodrugs of Oligonucleotides: The Acylox

Prodrugs of Oligonucleotides: The Acyloxyalkyl Esters of Oligodeoxyribonucleoside Phosphorothioates

✍ R.P. Iyer; D. Yu; S. Agrawal 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 933 KB

In model studies toward development of prodrugs of oligonucleoside phosphorothioates, \(R_{\mathrm{p}}\) and \(S_{\mathrm{p}}, S\)-alkyl phosphorothiolates 3a-d were prepared by chemoselective S-alkylation of \(R_{\mathrm{p}}\) and \(S_{\mathrm{p}}\) dinucleoside phosphorothioate 2 with iodoalkyl ac

Hydrolysis of carboxylate and phosphate

Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media

✍ Namrata Singh; Kallol K. Ghosh; Jan Marek; Kamil Kuca 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

## Abstract The reactions of __p__‐nitrophenyl acetate (PNPA) with a series of monopyridinium oximes, viz. 2‐PAM (2‐hydroxyiminomethyl‐1‐methylpyridinium iodide), 3‐PAM (3‐hydroxyiminomethyl‐1‐methylpyridinium iodide), and 4‐PAM (4‐hydroxyiminomethyl‐1‐methylpyridinium iodide) have been studied in

Synthesis and kinetic study of hydrolysi

Synthesis and kinetic study of hydrolysis of di-2-chloroaniline phosphate ester in acidic medium

✍ Nitin Choure; S. A. Bhoite 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB

## Abstract The kinetics and mechanism of the acid‐catalyzed hydrolysis of di‐2‐chloroaniline phosphate ester were studied in 0.5–7.0 mol dm^−3^ hydrochloric acid at 80°C in 20/80 (v/v) dioxane–water medium. The log rate profile shows rate maximum at 4.0 mol dm^−3^ hydrochloric acid. The results sh