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The tetramethylguanidine catalyzed Baylis–Hillman reaction: Effects of co-catalysts and alcohol solvents on reaction rate

✍ Scribed by Richard S. Grainger; Nicholas E. Leadbeater; Anna Masdéu Pàmies


Book ID
118629814
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
65 KB
Volume
3
Category
Article
ISSN
1566-7367

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Effect of polar aprotic solvents and org
✍ S. Dabi; A. Zilkha 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 310 KB

DMF and DMSO catalyse the reaction of butanol with PhNCO but inhibit that with aliphatic isocyanates, due to formation of an active 1 : 1 charge transfer complex with the aromatic isocyanate. Similarity was found in the mode of catalysis of the urethane reaction with these solvents to that with tert