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The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases

✍ Scribed by Katrien Backers; Daniel Blero; Nathalie Paternotte; Jing Zhang; Christophe Erneux

Book ID
114098862
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
186 KB
Volume
43
Category
Article
ISSN
0065-2571

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✍ Annemarie Gagnon; Yulia Artemenko; Thet Crapper; Alexander Sorisky πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 266 KB

## Abstract The role of the inositol lipid 5‐phosphatase (SHIP2) in preadipocyte signaling is not known. Although overexpression of SHIP2 inhibited proliferation and ^3^H‐thymidine incorporation in 3T3‐L1 preadipocytes, there was no effect on insulin‐induced adipogenesis. Insulin promoted SHIP2 tyr