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The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation

✍ Scribed by Dosso, Sara; Grande, Enrique; Barriuso, Jorge; Castellano, Daniel; Tabernero, Josep; Capdevila, Jaume


Book ID
121597277
Publisher
Springer
Year
2013
Tongue
English
Weight
434 KB
Volume
32
Category
Article
ISSN
0167-7659

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## Abstract ## BACKGROUND. The mammalian target of rapamycin (mTOR) pathway is up‐regulated in many human cancers, and agents targeting the mTOR pathway are in various stages of clinical development. The goal of the study was to evaluate the potential and limitations of targeting the mTOR pathway