The systemic approach to the stability and plasticity of neurophysiological processes during adaptive brain activity

X-ray powder diffractometry of intact fi

X-ray powder diffractometry of intact film coated tablets—An approach to monitor the physical form of the active pharmaceutical ingredient during processing and storage

✍ Hiroyuki Yamada; Raj Suryanarayanan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

The antiviral compound, 2-amino-6-(4-methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl)ester (MCC-478), can exist in several anhydrous polymorphic forms and also as a hemihydrate. The XRD patterns of the tablets, containing each form of the active pharmaceutical ingredi