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The synthesis of tetrahydroisoquinolines from 1,4-dihydro-3 (2H)-isoquinolones

✍ Scribed by Jacob Finkelstein; Arnold Brossi


Book ID
112121604
Publisher
Journal of Heterocyclic Chemistry
Year
1967
Tongue
English
Weight
315 KB
Volume
4
Category
Article
ISSN
0022-152X

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A new procedure for the synthesis of 2,3-diaryl-3,4-dihydro-4-hydroxy-1(2H)isoquinolones is described rn which the cis-isomer predominates. Dehydration leads to 2,4-diarylisocarbostyrils. The synthetic utility of metallated phthalide derivatives has recently received considerable attention for the