✦ LIBER ✦
The Synthesis of Pseudo-Geminal, Pseudo-Ortho and Ortho Hydroxy-oxazolinyl[2.2]paracyclophanes for Use as Ligands in Asymmetric Catalysis
✍ Scribed by Carsten Bolm; Daniel K. Whelligan
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 145 KB
- Volume
- 348
- Category
- Article
- ISSN
- 1615-4150
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✦ Synopsis
Abstract
Synthetic routes to pseudo‐geminal, pseudo‐ortho and ortho hydroxy‐oxazolinyl[2.2]paracyclophanes (and the diastereoisomers of each) for use as N,O ligands in asymmetric catalysis have been devised. The substitution pattern was found to have a strong effect on the rate and enantioselectivity of the formed catalyst in the addition of diethylzinc to benzaldehyde.