A general synthesis of alkynyl orthoesters leads to intermediates that couple with 2-trimethylsilyloxy-4-methoxyfuran to give compounds from which epoxypiperolide and isomers are available as well as all piperolide isomers. Piperolide II, epoxypiperolide 2 1a,2 and (-)-threo-7,8-dihydroxypiperolide
✦ LIBER ✦
The synthesis of piperolide and related compounds
✍ Scribed by Andrew Pelter; Miqdad T. Ayoub; Jutta Schultz; Rudolf Hänsel; Dieter Reinhardt
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 196 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
An efflclent synthesis of methyl tetronate, of use as a synthon for butenollde productlon, 1s outllned.
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