𝔖 Bobbio Scriptorium
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The Synthesis of Physiologically Active Peptides

✍ Scribed by Dr. Rolf Geiger

Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
898 KB
Volume
10
Category
Article
ISSN
0044-8249

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✦ Synopsis

Abstract

In addition to the classical protective groups and linkage.methods for the synthesis of peptides, there are now a number of new techniques that allow the synthesis of fairly long peptide chains without racemization. In the present progress report, the diagnostic and therapeutic importance of the analogs obtainable by chemical synthesis is illustrated by some examples, particularly from the field of the peptide hormones secreted by the neurohypophysis, oxytocin and vasopressin, as well as corticotropins and releasing hormones. With the advance of synthesis technique, it will become possible to include fairly complicated molecules, such as insulin and even enzymes in such considerations.

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