𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis of optically active building blocks carrying an α, α-dihalogeno-β, β, β-trifluoroethyl group

✍ Scribed by Tomoya Kitazume; Takeshi Ohnogi; Jenq Tain Lin; Takashi Yamazaki; Keizo Ito


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
499 KB
Volume
42
Category
Article
ISSN
0022-1139

No coin nor oath required. For personal study only.

✦ Synopsis


Optically active molecules with a.a-dihalogeno-8,8.atrifluoroethyl groups were prepared by the microbial hydrolysis of the corresponding esters.


📜 SIMILAR VOLUMES


Cu-catalyzed asymmetric conjugate reduct
✍ Zheng-Chao Duan; Xiang-Ping Hu; Dao-Yong Wang; Sai-Bo Yu; Zhuo Zheng 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 249 KB

A series of chiral alkylphosphonates bearing b-stereogenic center were synthesized in good enantioselectivities (up to 95% ee) via the CuH-catalyzed asymmetric conjugate reduction of b-substituted a,b-unsaturated phosphonates under optimal conditions using Cu(OAc) 2 ÁH 2 O as the copper source, (R)-