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The synthesis of mevalonic acid by non-particulate avian and mammalian enzyme systems

✍ Scribed by Jonathan Brodie; John W. Porter


Book ID
118847416
Publisher
Elsevier Science
Year
1960
Tongue
English
Weight
233 KB
Volume
3
Category
Article
ISSN
0006-291X

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## Abstract In this paper, we describe the structure‐based design, synthesis, and biological evaluation of cytosine derivatives and analogues that inhibit IspF, an enzyme in the non‐mevalonate pathway of isoprenoid biosynthesis. This pathway is responsible for the biosynthesis of the C~5~ precursor