The synthesis of highly functionalized seven-membered allyl ethers using palladium-catalyzed alkoxyallylation of activated olefins and ring-closing olefin metathesis

✍ Scribed by Roger L Xie; James R Hauske

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 83 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01834-7

✦ Synopsis

The investigation of palladium-catalyzed alkoxyallylation of activated olefins, followed by ring-closing metathesis to synthesize functionalized seven-membered ring allyl ethers is described. The influence of the olefin substituents on the diastereoselectivity of the alkoxyallylation has also been examined.