The synthesis of enantiomerically pure 4-substituted [2.2]paracyclophane derivatives by sulfoxide–metal exchange
✍ Scribed by Hitchcock, Peter B.; Rowlands, Gareth J.; Parmar, Rakesh
- Book ID
- 121508405
- Publisher
- Royal Society of Chemistry
- Year
- 2005
- Tongue
- English
- Weight
- 274 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1359-7345
- DOI
- 10.1039/B507394D
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📜 SIMILAR VOLUMES
Highly diastereoselective nucleophilic addition reactions of organometallic reagents to formyl[2.2]paracyclophane derivatives which were ortho-substituted by hydroxy-, alkoxy-and trimethylsilyloxy-groups are reported. The absolute configuration of the newly formed secondary alcohols is assigned on t
## Various N-(R)-(+)-(tx-methylbenzyl)-(2R,3R )-disubstituted aziridines were prepared by intramolecular cyclization. The regioselective reduction of the ring C(3)-N bond in the presence of (Boc)~O by catalytic hydrogenation with atmospheric pressure of hydrogen provides (D)-phenylalaninol analogu