Radiochemical synthesis of dl-canaline a
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Gerald A. Rosenthal; Deborah Thomas
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Article
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1984
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Elsevier Science
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English
β 361 KB
A procedure is available for the production of DL-[carboxy-14C]canaline from [14C]cyanide by reaction of ethyl N-hydroxyacetimidate and acrolein to form ethyl N-[3-oxopropoxy]acetimidate. The reaction product is converted to the nitrile and then to the hydantoin derivative of DL-canaline; alkaline h