The synthesis of deuterated methyl methacrylates

✍ Scribed by G. Ayrey; D. J. D. Wong

• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: French
• Weight: 286 KB
• Volume: 14
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580140619

✦ Synopsis

2 Methyl esters o f : 2-methyl [3-H21prop-2-enoic a c i d (methyl methacrylate-d2 , C02=C(CH31C02CH3) and 2-[Me-2 H31methylprop-2-enoic a c i d (methyl methacrylate-dg , CH2=C(C031C02CH31 were prepared i n h i g h y i e l d under m i l d c o n d i t i o n s from carbomethoxymethyltriphenylphosphonium bromide i n a new a p p l i c a t i o n of t h e W i t t i g r e a c t i o n . The methyl e s t e r of 2-methylprop [ H51 -2-enoic a c i d (methyl methacrylate-d5 , CO,-C(CD IC02CH31 was prepared from acetone-dg v i a t h e acetone cyanohydrin method.