Synthesis of regioisomeric 6,9-(chlorofl
β
A. Paul Krapcho; Cynthia E. Gallagher; Abdelhakim Hammach; Michael Ellis; Ernest
π
Article
π
1997
π
Journal of Heterocyclic Chemistry
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English
β 465 KB
## Abstract Treatment of difluoro or chloro fluoroβsubstituted benzyl bromides 5aβc with zinc dust in tetrahydroβfuran leads to the corresponding benzylic zinc bromides 6aβc. These organometallics on treatment with chlorosubstituted heterocyclic esters 4A and 4B mediated by nickel catalysis undergo