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The synthesis of 5-arylpyrrolo[3,2-b]pyridines and 7-arylpyrrolo[3,2-b]pyridines: Addition of 3-aminopyrroles to aryl enaminones

✍ Scribed by Gary H. Birnberg; William J. Fanshawe; Gerardo D. Francisco; Joseph W. Epstein


Book ID
112131326
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
413 KB
Volume
32
Category
Article
ISSN
0022-152X

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Synthesis of some new bipyridines, thien
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## Abstract Cyclocondensation of cyanoacetamide and cyanothioacetamide with sodium salt of 3‐hydroxy‐1‐(pyridin‐3‐yl)prop‐2‐en‐1‐one gave 6‐oxo‐[2,3β€²]bipyridine **5a** and 6‐thioxo‐[2,3β€²]bipyridine **5b** derivatives, respectively. Compound **5b** upon treatment with different methylenes **8** gave