𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Synthesis of 3,5-Diamino-1,2,4-oxadiazoles. 1st Communication

✍ Scribed by Jefferson W. Tilley; Henri Ramuz

Publisher
John Wiley and Sons
Year
1980
Tongue
German
Weight
472 KB
Volume
63
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Reaction of the 1‐substituted‐3‐cyano‐isothioureas 6 with hydroxylamine gave mixtures of the 5‐amino‐3‐substituted‐amino‐1,2,4‐oxadiazoles 1 and the isomeric 3‐amino‐5‐substituted‐amino‐1,2,4‐oxadiazoles 8 in which 1 usually predominated. The structural assignment of these products is discussed. In a second method, the 2‐hydroxy‐1‐methyl‐1‐phenyl‐guanidine 15 was converted to the corresponding 3‐disubstituted‐amino‐5‐trichloromethyl‐1,2,4‐oxadiazole 16, a precursor to the 5‐amino derivatives 17 by nucleophilic displacement of the trichloromethyl group.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Macroc
ChemInform Abstract: Synthesis of Macrocyclic Systems from 4,4′-Diamino-3,3′-bi-1,2,5-oxadiazole and 3(4)-Amino-4(3)-(4-amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazole 2-Oxides.
✍ M. A. Epishina; A. S. Kulikov; N. N. Makhova 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v