## Abstract Indicine __N__βoxide, an antitumor agent possessing an unusual type of potential alkylating capacity, was recently selected for clinical trial. Radioactiveβlabelled indicine __N__βoxide was sought for studies of its biological properties relating to antitumor activity and toxicity. Avai
The synthesis of 13N-labelled nitrous oxide
β Scribed by R.J. Nickles; S.J. Gatley; R.D. Hichwa; D.J. Simpkin; J.L. Martin
- Publisher
- Elsevier Science
- Year
- 1978
- Weight
- 219 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0020-708X
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2 -~h l o r o -[ l -~~C ] p r o p i o n y l chloride, phenyl-2-chloro-[l-13Clpropionate, 2-chloro-[ 1-13C] propan-1-01. 1-methyl-[ 2-I3C I ethylene oxide. SUMMARY 13 l-Methyl-[2-Clethylene oxide (I) is prepared in a four-step synthesis, I J starting from [l-Clpropionic acid. A method for an efficien
1 3 e n r i c h e d n -a l k y l c h l o r o s i l a n e s w i t h l a b e l i nc o r p o r a t i o n a t s e l e c t i v e p o s i t i o n s a l o n g t h e a l k y l c h a i n s . Compounds w h i c h w e r e p r e p a r e d w e r e : n -n o n y l t r i c h l o r o s i 1 a n e -1 -' 3 C n -d o d e
## Abstract The introduction of several ^13^Cβatoms in the alkane chain is described. A maximum number of compounds, with up to six ^13^C labels, are obtained with a minimum of different reactions.