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The Synthesis of 1-R-5-R'-5-Phenylhydantoins

โœ Scribed by Long, Loren M.; Miller, C. A.; Troutman, H. D.


Book ID
126000354
Publisher
American Chemical Society
Year
1948
Tongue
English
Weight
466 KB
Volume
70
Category
Article
ISSN
0002-7863

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Synthesis of (โˆ’)-(1S,5R)- and (+)-(1R,5S
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The synthesis of enantiomerically pure (-)-(1S,5R)-1-trifluoromethyl frontalin 7 starting from (-)-(1R)-menthyl (S)-toluene-4-sulfinate, 5-pentenylmagnesium bromide and methyl trifluoroacetate is described. The synthetic procedures to obtain the enantiomer (+)-(1R,5S)-7 are also mentioned. Absolute