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The synthesis and structure of an n-terminal dodecanoic acid conjugate of α-conotoxin MII

✍ Scribed by Joanne Blanchfield; Julie Dutton; Ron Hogg; David Craik; David Adams; Richard Lewis; Paul Alewood; Istvan Toth


Book ID
110349956
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
159 KB
Volume
8
Category
Article
ISSN
1573-3149

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✍ Charles W. Jefford; James McNulty; Zhi-Hui Lu; Jian Bo Wang 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 German ⚖ 1016 KB

## Abstract L‐Aspartic acid by tosylation, anhydride formation, and reduction with NaBH~4~ was converted into (3__S__)‐3‐(tosylamino)butan‐4‐olide (8; __Scheme 1__). Tretment of 8 with ethanolic trimethylsilyl iodide gave the __N__‐protected deoxy‐iodo‐β‐homoserine ethyl ester 9. The latter, on suc