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The Synthesis and Reactions of Unsaturated N-Methylolamides 1,2,3

✍ Scribed by Feuer, Henry; Lynch, Una E.


Book ID
120287830
Publisher
American Chemical Society
Year
1953
Tongue
English
Weight
438 KB
Volume
75
Category
Article
ISSN
0002-7863

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The 1',2'-unsaturated 2',3'-secoadenosine and 2',3'-secouridine analogues were synthesized by the regioselective elimination of the corresponding 2',3'-ditosylates, 2 and 18, respectively, under basic conditions. The observed regioselectivity may be explained by the higher acidity and, hence, prefer