𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis and conformational analysis of perhydro-1,2,4-triazines and perhydro-1,3,4-thiadiazines and a note on

✍ Scribed by Alan R. Katritzky; Ranjan C. Patel; David M. Read

Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
261 KB
Volume
18
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

1,2,4-Triazanes and 1,3,4_thiadiazanes are previously unknown classes of compound:

we have now synthesised representatives of each (Scheme 1) by methods which utilise thiiran n and N-methylaziridine and are extensions of our previously reported' synthesis of the 1,3,4-oxadiazane ring system.

πŸ“œ SIMILAR VOLUMES

A facile synthesis of substituted perhyd
A facile synthesis of substituted perhydro-1,3-thiazin-4-ones and 2-thioxoperhydro-4-pyrimidinones
✍ Elghandour, Ahmed Hafez Hussien ;Ramiz, Mahmound Mohamed Mahfouz ;Ghozlan, Said πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 419 KB

Depending on the reaction conditions eithcr 2.6-disubstitutcd 2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones 4 or 1,6-disubstitutcd 2-thiouracils 5 are readily prepared by base-catalyzcd cyclization of N-propenoylthioureas 3. Compounds 5 could also bc obtained by Dimroth-type rearrangement of 1,3-thiazin-

Synthesis and anti-inflammatory evaluati
Synthesis and anti-inflammatory evaluation of 3-methylthio-1,2,4-triazines, 3-alkoxy-1,2,4-triazines, and 3-aryloxy-1,2,4-triazines
✍ William P. Heilman; R. D. Heilman; James A. Scozzie; R. J. Wayner; James M. Gull πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 723 KB

To develop nonacidic, nonsteroidal anti-inflammatory agents without GI complications, a series of asymmetric triazines was synthesized and evaluated for anti-inflammatory efficacy in the carrageenan-induced pedal edema assay. Toxicity was estimated by determination of approximate LD50 values in mice