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The synthesis and chemistry of azolenines. Part 8. The Paal-Knorr reaction with cyclic 2-(acylmethyl)-2-alkyl-1,3-diketones: isolation of 1-acyl-1H-pyrroles via rearrangement

โœ Scribed by Maini, Prem Nath; Sammes, Michael P.; Katritzky, Alan R.


Book ID
120060909
Publisher
Royal Society of Chemistry
Year
1988
Weight
756 KB
Volume
2
Category
Article
ISSN
1472-7781

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The synthesis and chemistry of azolenine
โœ Pak-Kan Chiu; Michael P. Sammes ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 462 KB

Treatment of 1,4-diketones with liquid ammonia gives high yields of isolable 2-hydroxy-3,4-dihydro-ZH-pyrrole intermediates. These intermediates, which do not appear to have been observed previously in the ?aal-norr s have been fully characterized by i-r. r and Hand nthesis with anaaonia, C n.m.r. s