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The synergism between metabotropic glutamate receptor activation and arachidonic acid on glutamate release is occluded by induction of long-term potentiation in the dentate gyrus

โœ Scribed by B. McGahon; M.A. Lynch


Book ID
116129330
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
886 KB
Volume
72
Category
Article
ISSN
0306-4522

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We have reported that arachidonic acid and the metabotropic glutamate receptor agonist, trans-1-amino-cyclopentyl-1,3-dicarboxylate (ACPD), act in synergy to increase release of glutamate from synaptosomes prepared from rat dentate gyrus. The observation that prior induction of LTP in perforant path