## Abstract Cytoarchitectural changes in the hippocampal formation have been prominent among the various neuropathological abnormalities reported in schizophrenia. Replicated positive findings include decreased neuronal size and alterations in presynaptic and dendritic markers. These findings, in t
The synaptic nature of the paroxysmal depolarizing shift in hippocampal neurons
โ Scribed by Dr Daniel Johnston; Thomas H. Brown
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 702 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We have monitored the incorporation of tritiated uridine into RNA by the giant neuron of the Aplysia abdominal ganglion. Synaptic stimulation evoking a mean of 3,000 impulses in the neuron increased incorporation by about 67%. Incorporation was proportional to the number of stimuli given and to the
The mitochondrial permeability transition (mPT) has been implicated in both excitotoxic and apoptotic neuronal cell death, despite the fact that it has not been previously identified in neurons. To study the mPT in hippocampal neurons, cultures were loaded with the mitochondrial dye JC-1 and observe
In studies of focal epilepsy it is frequently assumed that the interictal spike is the elementary form of epileptic activity and that seizure, or ictal, episodes evolve by temporal summation and spatial expansion of interictal paroxysms. We examined this hypothesis in an in vitro model of acute foca
The cytokine tumor necrosis factor-โฃ (TNF), well-known for its roles in cellular responses to tissue injury, has recently been shown to be produced in response to physiological activity in neuronal circuits. TNF stimulates receptors in neurons linked to the activation of the transcription factor NF-