Syk, a nonreceptor type of protein tyrosine kinase widely expressed in hematopoietic cells, is a candidate suppressor gene in human breast cancer. Reduced expression of Syk protein is correlated with poor prognosis, while its overexpression can reduce the malignant phenotype of breast cancer cells.
β¦ LIBER β¦
The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells
β Scribed by Coopman, Peter J. P.; Do, Michael T. H.; Barth, Mara; Bowden, Emma T.; Hayes, Andrew J.; Basyuk, Eugenia; Blancato, Jan K.; Vezza, Phyllis R.; McLeskey, Sandra W.; Mangeat, Paul H.; Mueller, Susette C.
- Book ID
- 109770520
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 428 KB
- Volume
- 406
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/35021086
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