The survival and developmental outcome of extremely low birthweight infants

✍ Scribed by Daniel Messinger; Jack Dolcourt; Jerald King; Anna Bodnar; Don Beck

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 707 KB
• Volume: 17
• Category: Article
• ISSN: 0163-9641
• DOI: 10.1002/(sici)1097-0355(199624)17:4<375::aid-imhj8>3.0.co;2-l

✦ Synopsis

The purpose of this retrospective study is to compare the factors affecting the survival and developmental outcome of examely low birthweight infants (ELBW, < 1,001 gms.). One hundred and forty of two hundred and twenty-three ELBW neonates (63%) from two Level LII NICUs born between 1986 and 1988 survived until discharge. Lower birthweight. 5-minute Apgar d 3, and no administration of surfactant were the best predictors of infant mortality as assessed via logistic regression (correct classification = 78%). The functioning of 34 of these infants was assessed at approximately 18 months of age with the Bayley Scales of Infant Development. Mean performance on the Mental Development Index (MDI) was 88.65 ? 21.75, with 35.3% and 20.6% of infants scoring. respectively, 1 (C85) and 2 (<70) standard deviations below the mean. Given survival, intraventricular hemorrhage (IVH, Grade 111 or IV) was the best predictor of M I performance as assessed via stepwise multiple regression (adjusted R2 =.23). Cerebral palsy affected one fifth of the sample and was also best predicted by IVH. Discussion focuses on the conceptual and practical implications of the finding that infant survival and infant developmental status were associated with different factors.

RESUMEN: El prop6sito de este estudio retrospectivo es comparar 10s factores que afectan la supervivencia y 10s resultados de desarrollo de infantes nacidos con un peso extremadamente bajo (ELBW, C 1,001 gms.). 140 de 223 ELBW reci6n nacidos (63%) de dos niveles IJI NICUs nacidos entre 1986 y 1988 sobrevivieron hasta que fueron dados de alta. Un peso m b bajo al momento del nacimiento, cinco minutos de aplicaci6n del sistema Apgar con un resultado de 53. y la falta de administracidn de surfactantes fueron 10s mejores indicadores de The research reported here was supported by a grant from the