✦ LIBER ✦

The substrate domain of BCAR1 is essential for anti-estrogen-resistant proliferation of human breast cancer cells

✍ Scribed by Arend Brinkman; Danielle de Jong; Sietske Tuinman; Najat Azaouagh; Ton van Agthoven; Lambert C. J. Dorssers

Publisher: Springer US
Year: 2009
Tongue: English
Weight: 400 KB
Volume: 120
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-009-0403-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Identification of a novel breast-cancer-

Identification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cells

✍ Lambert C.J. Dorssers; Jos Veldscholte 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 177 KB 👁 2 views

Development of anti-estrogen resistance limits the benefit of endocrine therapy of breast cancer. The mechanistic basis for resistance to the anti-estrogen tamoxifen may involve (epi)genetic alterations within tumor cells. We have initiated a random search for genes allowing estrogen-dependent ZR-75

AND-34/BCAR3 differs from other NSP homo

AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology

✍ Richard I. Near; Yujun Zhang; Anthony Makkinje; Pierre Vanden Borre; Adam Lerner 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract Over‐expression of AND‐34/BCAR3/NSP2 (BCAR3) or its binding‐partner p130Cas/BCAR1 generates anti‐estrogen resistance in human breast cancer lines. Here, we have compared BCAR3 to two related homologs, NSP1 and NSP3/CHAT/SHEP, with regards to expression, anti‐estrogen resistance, and sig

Increased expression of cytochrome p450

Increased expression of cytochrome p450 1A1 and 1B1 genes in anti-estrogen–resistant human breast cancer cell lines

✍ Bettina L. Brockdorff; Jan Skouv; Birgit E. Reiter; Anne E. Lykkesfeldt 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 105 KB 👁 1 views

Resistance of human breast-cancer cells

Resistance of human breast-cancer cells to the pure steroidal anti-estrogen ICI 182,780 is not associated with a general loss of estrogen-receptor expression or lack of estrogen responsiveness

✍ Søren S. Larsen; Mogens W. Madsen; Bettina L. Jensen; Anne E. Lykkesfeldt 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 145 KB 👁 3 views

To elucidate the mechanisms responsible for the development of anti-estrogen resistance, we have cloned and established 3 stable ICI-182,780-resistant sub-lines, MCF-7/182 R -1, MCF-7/182 R -6 and MCF-7/182 R -7 from the estrogen-receptor(ER)-positive and estrogen-responsive human breastcancer MCF-7

Activation of ErbB3, EGFR and Erk is ess

Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant

✍ Thomas Frogne; Rikke V. Benjaminsen; Katrine Sonne-Hansen; Boe S. Sorensen; Ebba 📂 Article 📅 2008 🏛 Springer US 🌐 English ⚖ 836 KB

Interleukin 1 (IL-1) production is not e

Interleukin 1 (IL-1) production is not essential for acquired resistance of human A375 melanoma cells to anti-proliferative effect of IL-1

✍ Saotomo Itoh; Hidetoshi Hayashi; Naoko Watanabe; Yoshiro Kobayashi; Takemasa Tak 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 817 KB

## FOR ACQUIRED RESISTANCE OF HUMAN A375 MELANOMA The proliferation of human melanoma cell line A375-6 is inhibited by interleukin I (IL-I). However, the cells acquired resistance to IL-I after a long period of culture. We have reported that 2 resistant subclones, A375-R8 and -R19, produced ILla c