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The subcellular distribution of tritiated 4-dimethylaminoazobenzene and 2-methyl-4-dimethylaminoazobenzene in rat liver and spleen following a single oral administration

✍ Scribed by A.E. Albert; G.P. Warwick


Book ID
113135316
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
209 KB
Volume
5
Category
Article
ISSN
0009-2797

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Male inbred Leeds strain rats were given single intragastric doses of 1200 mg/kg of 3'-methyl-4-dimethylaminoazobenzene, autoprotective against liver necrosis and then sacrificed at intervals up to 14 months. About 40 per cent of the animals died, apparently as a result of pancreatic necrosis, betwe