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The Study of Protein Conformation in Solution Via Direct Sampling by Desorption Electrospray Ionization Mass Spectrometry

✍ Scribed by Zhixin Miao; Shiyong Wu; Hao Chen

Book ID: 108158589
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 592 KB
Volume: 21
Category: Article
ISSN: 1044-0305
DOI: 10.1016/j.jasms.2010.06.003

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## Abstract The influence of tertiary structure on the electrospray ionization mass spectra of proteins is a well known and broadly exploited phenomenon. However, the underlying mechanism is not well understood. This paper discusses the bases and the implications of the two current hypotheses (solv