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The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface

✍ Scribed by Camerino, Michelle A.; Zhong, Nan; Dong, Aiping; Dickson, Bradley M.; James, Lindsey I.; Baughman, Brandi M.; Norris, Jacqueline L.; Kireev, Dmitri B.; Janzen, William P.; Arrowsmith, Cheryl H.; Frye, Stephen V.

Book ID
121450616
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
649 KB
Volume
4
Category
Article
ISSN
2040-2503

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## Abstract The human __L3MBTL__ gene is located in 20q12, a region that is commonly deleted in myeloproliferative disorders (MPD), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML). __L3MBTL__ is highly homologous to the D‐lethal(3) malignant brain tumor [__D‐l(3)mbt__] gene, which