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The Structure of the Fusion Glycoprotein of Newcastle Disease Virus Suggests a Novel Paradigm for the Molecular Mechanism of Membrane Fusion

✍ Scribed by Lin Chen; Jeffrey J Gorman; Jenny McKimm-Breschkin; Lynne J Lawrence; Peter A Tulloch; Brian J Smith; Peter M Colman; Michael C Lawrence


Book ID
114328914
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
665 KB
Volume
9
Category
Article
ISSN
0969-2126

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## Abstract Varicella‐zoster virus (VZV) is well known for its propensity to cause polykaryons (syncytia) in the vesicles within infected skin. Similarly in cultured cells, VZV induces extensive syncytial formation by virus‐mediated cell‐to‐cell fusion. Statistical analyses of fusion parameters dem