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The Structure of the Dynein Motor Domain

โœ Scribed by Carter, Andrew P.


Book ID
119209417
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
35 KB
Volume
102
Category
Article
ISSN
0006-3495

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The highly conserved lysine residue in the putative hydrolytic ATP-binding motif of the yeast cytoplasmic dynein heavy chain was replaced with leucine. The mutation was generated by a two-stage transformation method designed for genomic site-directed mutagenesis. Preliminary observations show that t