The Structure of the Cactus Sterol Macdougallin (14α-Methyl-[UNK]-Cholestene-3β,6α-Diol)--A Novel Link in Sterol Biogenesis

Inhibitors of sterol synthesis. Concerni

Inhibitors of sterol synthesis. Concerning the structure of 15β-methyl-5α,14β-cholest-7-ene-3β,15α-diol, an inhibitor of cholesterol biosynthesis

✍ Samuel T. Bowen; Edward J. Parish; William K. Wilson; George J. Schroepfer Jr.; 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 399 KB

The chemical synthesis of 3 beta-p-bromobenzoyloxy-15 beta-methyl-5 alpha,14 beta-cholest-7-en-15 alpha-ol from 15 beta-methyl-5 alpha, 14 beta-cholest-7-ene-3 beta,15 alpha-diol is described. The structure of the former compound was unambiguously determined by X-ray crystallographic analysis. The s