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The Structure of the Bovine Protein Tyrosine Phosphatase Dimer Reveals a Potential Self-Regulation Mechanism †,‡

✍ Scribed by Tabernero, Lydia; Evans, Bornadata N.; Tishmack, Patrick A.; Van Etten, Robert L.; Stauffacher, Cynthia V.


Book ID
127342988
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
531 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract This study tested the hypothesis that an osteoclastic protein‐tyrosine phosphatase, PTP‐oc, enhances osteoclast activity through c‐Src activation. The effects of several resorption activators and inhibitors on PTP‐oc expression, resorption activity, and c‐Src activation were determined