The structure of the antibiotic K16. I. The dipeptide side chain.
β Scribed by J.G. Batelaan; J.W.F.K. Barnick; J.L. van der Baan; F. Bickelhaupt
- Book ID
- 108384444
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 186 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
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The relative configurations in the diepoxide side chain of the antibiotic hedamycin have been shown to be rel-(14R,16S,17R,18S). The structure of the antibiotic hedamycin (1) has recently been elucidated in our laboratory. 2-4) However, the relative configurations in the unique diepoxide side chain
## Abstract We compare in this contribution the aggregation and the rotational sideβchain isomerism of the diastereomeric cyclodipeptides phenylalanineβpipecolic acid (1, 2) with those previously observed^1^ in the parent DKP's, containing the 4βthiapipecolic acid moieties instead. Concomitantly wi