𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Structure of the Antibiotic Hedamycin. I. Chemical, Physical and Spectral Properties

✍ Scribed by Urs Séquin; Colin T. Bedford; Sung K. Chung; A. Ian Scott

Publisher
John Wiley and Sons
Year
1977
Tongue
German
Weight
615 KB
Volume
60
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Interpretation of the chemical and spectral (IR., UV., ^1^H‐ and ^13^C‐NMR.) properties of the antitumor antibiotic hedamycin (C~41~H~50~N~2~O~11~) suggests that the molecule contains a methyl substituted 1‐hydroxyanthraquinone nucleus, an α, β‐unsaturated ketone, two sugar‐like tetrahydropyran rings (4 and 8) and an aliphatic chain 2, presumably with an epoxy group (see the Scheme).

📜 SIMILAR VOLUMES

The Structure of the Antibiotic Hedamyci
The Structure of the Antibiotic Hedamycin. V. Crystal structure and absolute configuration
✍ Margareta Zehnder; Urs Séquin; Heinz Nadig 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 German ⚖ 506 KB

The crystal structure of the antibiotic hedamycin (1) has been solved by direct method and refined by least squares techniques to R=0.091 for 2289 of 2643 independent reflexions. Crystals of C4,HS,,N,0 are orthorhombic, space group P2,2,2' with lattice parameters a=24.239 (12), b=21.440 (lo), c=7.36

The Structures of Some Products from the
The Structures of Some Products from the Photodegradation of the Pluramycin Antibiotics Hedamycin and Kidamycin
✍ Andreas Fredenhagen; Urs Séquin 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 German ⚖ 668 KB

## Abstract The photolability of the antitumor antibiotic hedamycin (**1**) was investigated by irradiation in different solvents in the presence or in the absence of oxygen. The products formed were separated chromatographically and their structures determined by NMR spectroscopy. Photolysis of **

Structure and physical properties of seg
Structure and physical properties of segmented polyurethane elastomers containing chemical crosslinks in the hard segment
✍ Zoran S. Petrović; Ivan Javni; Vladimir Divjaković 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB 👁 2 views

Two series of segmented polyurethanes, one containing 50% soft segments and the other with 70% soft segments were synthesized. Chemical crosslinks were introduced through the hard segment in a controlled way. Chemical polyurethane networks were characterized by swelling. The effect of the degree of

The mesoglea of hydra. I. Physical and h
The mesoglea of hydra. I. Physical and histochemical properties
✍ Hausman, Robert E. ;Burnett, Allison L. 📂 Article 📅 1969 🏛 John Wiley and Sons 🌐 English ⚖ 567 KB

The mesoglea of Hydra serves both as a skeleton and as a substratum for cell migration. These functions are made possible in Hydra pseudoligactis by a system of fibers that run along the body column, parallel to the oral-aboral axis, and perpendicular to the oral-aboral axis. The fibers are either a