The structure of palasonin

✍ Scribed by Richard J. Bochis; Michael H. Fisher

• Book ID: 104249633
• Publisher: Elsevier Science
• Year: 1968
• Tongue: French
• Weight: 138 KB
• Volume: 9
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)99067-7

✦ Synopsis

Palasonin, ' . a principle isolated from the seeds of Butea frondosa, has been shown to be exo-cis-3,6-epoxy-l-methylhexahydrophthalic anhydride (desmethyl--cantharidin) (I). Raj and Kurup (1) recently examined the seeds of Butea frondosa, an Indian tree, for anthelmintic substances and described the isolation of a compound m.p. 106-108' which they named palasonin. Elemental analysis, IR and NMR spectra, and the formation of several derivatives led them to the conclusion that palasonin had the molecular formula Cl6 H 0 and possessed an orthodicarboxylic acid, a 22 6 lactone, and a gem dimethyl group. By a similar procedure we obtained a compound m.p. 109-111".