Identification of anhydroecgonine methyl
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Anabel S. FandiΓ±o; Michael Karas; Stefan W. Toennes; Gerold Kauert
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Article
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2002
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John Wiley and Sons
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English
β 179 KB
Cocaine is transformed into hepatotoxic metabolites through oxidative pathways. For anhydroecgonine methyl ester (AEME), the main constituent in crack smoke, the oxidative metabolism has not been studied. Therefore, incubation of AEME with rat liver microsomes was performed and a metabolite of AEME,