The structure of a tremorgenic metabolite from aspergillus fumigatus fres., fumitremorgin a.
โ Scribed by Mikio Yamazaki; Haruhiro Fujimoto; Takao Kawasaki
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 203 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Gliotoxin G, the tetrasulphide analogue of gliotoxin has been characterized from a laboratory isolate of Aspergillus fumigatus.
Reoeived in USA 5 Nay 1975; received ia UK for publication 27 Nay 1975) The fungus Penicillium paxilli Bainier produces a metabolite paxilline (Ca7Hs3N04) capable of inducing severe tremors in mice with an EDso of 25 mg/kg.
In the course of a continuing search for indole metabolites in mycelia of Asp. rubsr, three new compounds named isoechinulin A, B and C were isolated and characterized. Based on the chemical and physicochemical evidences, the structures of these compounds have been established as 1, 2 and 2, respect