The structure of a ring-D-bridged steroid
β Scribed by Birnbaum, G. I.
- Book ID
- 117858173
- Publisher
- International Union of Crystallography
- Year
- 1973
- Weight
- 834 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0567-7408
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π SIMILAR VOLUMES
The chemical shifts of the CI,-and C,s-hydrogens of 30 14a,l7a-bridged 20-ketopregnanes and of four 14a, 17a-bridged 17-cyanoandrostanes were correlated by means of additive substituent constants. Because the bridged D-ring of these steroids is a substituted bicyclo[2.2.l]Iieptaiie sytem, attempts w
## Abstract In alkaline medium, 17Ξ²βhydroxyβ15β(hydroxymethylene)androstβ5βenβ16βone (2a) is cleaved in two ways to give Dβ__seco__ compounds. Dilute bases in protic solvents cause 1,3βdicarbonyl splitting to the 15βformylβ15,16β__seco__β16βoic acid 3, while the use of sodium methanolate in benzene