Molecular mechanics simulations of a con
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Oliver S. Smart; John Akins; Dr. David M. Blow
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Article
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1992
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John Wiley and Sons
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English
β 946 KB
## Abstract A proposed reaction mechanism for the enzyme Dβxylose isomerase involves the ring opening of the cyclic substrate with a subsequent conformational rearrangement to an extended openβchain form. Restrained energy minimization was used to simulate the rearrangement. In the ringβopening ste